Neurology and pain

Companies

• AC Immune SA (ACIU)Thesis Intact

  Neuroinflammation, Parkinson's disease, Alzheimer's disease, Amyotrophic lateral sclerosis

• Acumen Pharmaceuticals (ABOS)Thesis Challenged

  Alzheimer's disease

• Alpha Cognition (ACOG)Thesis Challenged

  Alzheimer's disease, Mild traumatic brain injury

• Alterity Therapeutics (ATHE)Thesis Challenged

  Multiple System Atrophy

• Alumis (ALMS)Thesis Challenged

  Multiple sclerosis, Parkinson's disease

• Amylyx Pharmaceuticals (AMLX)Thesis Intact

  Amyotrophic lateral sclerosis

• Anavex Life Sciences (AVXL)Thesis Broken

  Rett syndrome, Fragile X syndrome, Alzheimer's disease

• ANI Pharmaceuticals (ANIP)Thesis Challenged

  Multiple sclerosis

• Annexon (ANNX)Thesis Intact

  Huntington's disease, Amyotrophic lateral sclerosis

• Aquestive Therapeutics (AQST)Thesis Challenged

  Epilepsy, Seizure clusters, Parkinson's disease, Lennox-gastaut syndrome, and 1 more

• Arcus Biosciences (RCUS)Thesis Intact

  Multiple sclerosis

• Arrowhead Pharmaceuticals (ARWR)Thesis Intact

  Alzheimer's disease, Parkinson's disease, Huntington's disease, Spinocerebellar ataxia type 2, and 3 more

• Autolus Therapeutics (AUTL)Thesis Intact

  Multiple sclerosis, Progressive multiple sclerosis

• Bicycle Therapeutics (BCYC)Thesis Challenged

  Central nervous system disease

• Biohaven (BHVN)Thesis Challenged

  Epilepsy, Focal epilepsy, Acute migraine, Parkinson's disease, and 1 more

• BioRestorative Therapies (BRTX)Thesis Challenged

  Cervical discogenic pain

• BridgeBio Pharma (BBIO)Thesis Intact

  Canavan disease

• CervoMed (CRVO)Thesis Challenged

  Ischemic stroke, Dementia with Lewy bodies, Amyotrophic lateral sclerosis, Nonfluent variant primary progressive aphasia

• ClearPoint Neuro (CLPT)Thesis Challenged

  Intracranial hemorrhage

• Clene (CLNN)Thesis Challenged

  Amyotrophic lateral sclerosis

• Contineum Therapeutics (CTNM)Thesis Challenged

  Chronic pain

• Coya Therapeutics (COYA)Thesis Intact

  Alzheimer's disease, Frontotemporal Dementia, Amyotrophic lateral sclerosis

• CRISPR Therapeutics (CRSP)Thesis Intact

  Multiple sclerosis, Stiff person syndrome, Neuromyelitis optica spectrum disorder, Myelin oligodendrocyte glycoprotein antibody-associated disease

• Design Therapeutics (DSGN)Thesis Intact

  Huntington's disease

• Eupraxia Pharmaceuticals (EPRX)Thesis Intact

  Knee osteoarthritis pain

• Fennec Pharmaceuticals (FENC)Thesis Intact

  Cisplatin-induced ototoxicity

• Gain Therapeutics (GANX)Thesis Challenged

  Parkinson's disease

• Grace Therapeutics (GRCE)Thesis Challenged

  Aneurysmal subarachnoid hemorrhage

• Harrow (HROW)Thesis Challenged

  Pain

• Heron Therapeutics (HRTX)Thesis Challenged

  Postoperative pain, Postoperative pain management

• INmune Bio (INMB)Thesis Challenged

  Alzheimer's disease

• Ionis Pharmaceuticals (IONS)Thesis Intact

  Angelman syndrome, Alexander disease

• Keros Therapeutics (KROS)Thesis Intact

  Amyotrophic lateral sclerosis

• Kiora Pharmaceuticals (KPRX)Thesis Intact

  Epilepsy, Exploratory CNS indications

• Kyverna Therapeutics (KYTX)Thesis Intact

  Stiff person syndrome, Progressive multiple sclerosis

• Lexeo Therapeutics (LXEO)Thesis Intact

  Alzheimer's disease

• Lineage Cell Therapeutics (LCTX)Thesis Intact

  Hearing loss, Spinal cord injury, Auditory neuropathy

• Lipocine (LPCN)Thesis Broken

  Essential Tremor

• MeiraGTx (MGTX)Thesis Intact

  Neuropathic pain, Parkinson's disease, Amyotrophic lateral sclerosis

• Mesoblast (MESO)Thesis Intact

  Chronic low back pain

• Monte Rosa Therapeutics (GLUE)Thesis Intact

  CNS inflammatory diseases

• Nektar Therapeutics (NKTR)Thesis Intact

  Multiple sclerosis

• NervGen Pharma (NGEN)Thesis Challenged

  Spinal cord injury, Chronic tetraplegia due to spinal cord injury

• Neumora Therapeutics (NMRA)Thesis Intact

  Alzheimer's disease, Parkinson's disease, Amyotrophic lateral sclerosis, Agitation associated with dementia due to Alzheimer's disease

• Neurogene (NGNE)Thesis Intact

  Rett syndrome

• NewAmsterdam Pharma Company (NAMS)Thesis Intact

  Alzheimer's disease

• NewcelX (NCEL)Thesis Challenged

  Multiple sclerosis, Amyotrophic lateral sclerosis, Neurodegenerative and metabolic disorders

• NextCure (NXTC)Thesis Broken

  Alzheimer's disease

• NRx Pharmaceuticals (NRXP)Thesis Challenged

  Anesthesia and pain (ANDA), Amyotrophic lateral sclerosis

• Ovid Therapeutics (OVID)Thesis Intact

  Infantile spasms, Lewy body dementia, Focal onset seizures, Photosensitive epilepsy, and 5 more

• Palatin Technologies (PTN)Thesis Challenged

  Prader-willi syndrome

• Passage Bio (PASG)Thesis Broken

  Huntington's disease, Frontotemporal dementia

• Praxis Precision Medicines (PRAX)Thesis Intact

  Epilepsy, Essential tremor, Focal onset seizures, Generalized epilepsy, and 7 more

• Precision BioSciences (DTIL)Thesis Intact

  Multiple sclerosis, Progressive Multiple Sclerosis

• ProMIS Neurosciences (PMN)Thesis Intact

  Parkinson's disease, Alzheimer's disease, Multiple system atrophy, Mild Alzheimer's disease, and 3 more

• ProQR Therapeutics (PRQR)Thesis Intact

  Rett syndrome

• Quoin Pharmaceuticals (QNRX)Thesis Intact

  Tuberous sclerosis complex

• Sarepta Therapeutics (SRPT)Thesis Challenged

  Huntington's disease

• Serina Therapeutics (SER)Thesis Challenged

  Parkinson's disease

• Stoke Therapeutics (STOK)Thesis Intact

  Dravet syndrome, Syngap1 haploinsufficiency, SYNGAP-1 genetic neurodevelopmental disease

• Taysha Gene Therapies (TSHA)Thesis Intact

  Tauopathy, Rett syndrome, Fragile x syndrome

• TG Therapeutics (TGTX)Thesis Intact

  Relapsing multiple sclerosis, Progressive multiple sclerosis, Relapsing forms of multiple sclerosis

• Tiziana Life Sciences (TLSA)Thesis Challenged

  Alzheimer's Disease, Multiple System Atrophy, Traumatic spinal cord injury, Amyotrophic lateral sclerosis, and 2 more

• Tonix Pharmaceuticals (TNXP)Thesis Challenged

  Migraine, Fibromyalgia, Neuropathic pain, Prader-Willi syndrome, and 1 more

• Ultragenyx Pharmaceutical (RARE)Thesis Challenged

  Angelman syndrome

• uniQure (QURE)Thesis Challenged

  Huntington's disease, Refractory mesial temporal lobe epilepsy

• Viking Therapeutics (VKTX)Thesis Intact

  X-linked adrenoleukodystrophy

• Xenon Pharmaceuticals (XENE)Thesis Challenged

  Pain, Epilepsy, Dravet syndrome, Focal onset seizures, and 1 more

Drug pages

RelutrigineUlixacaltamideObecabtagene autoleucel (obe-cel)RexaceractMivocabtagene autoleucel (miv-cel)

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