Obesity, diabetes and heart disease

Companies

• Adagio Medical (ADGM)Thesis Challenged

  Ventricular tachycardia, Sustained monomorphic ventricular tachycardia

• Amylyx Pharmaceuticals (AMLX)Thesis Intact

  Post-bariatric hypoglycemia

• Arrowhead Pharmaceuticals (ARWR)Thesis Intact

  Obesity, Mixed hyperlipidemia, Severe hypertriglyceridemia, Familial chylomicronemia syndrome, and 2 more

• Ascendis Pharma (ASND)Thesis Challenged

  Obesity, Metabolic and cardiovascular diseases

• Bicycle Therapeutics (BCYC)Thesis Challenged

  Dilated cardiomyopathy

• BioAge Labs (BIOA)Thesis Intact

  Obesity

• Biohaven (BHVN)Thesis Challenged

  Obesity

• BioRestorative Therapies (BRTX)Thesis Challenged

  Obesity, Type 2 diabetes

• BridgeBio Pharma (BBIO)Thesis Intact

  ATTR-CM

• Corbus Pharmaceuticals (CRBP)Thesis Intact

  Obesity

• CRISPR Therapeutics (CRSP)Thesis Intact

  Hypertension, Type 1 diabetes, Thromboembolic disease, Elevated lipoprotein(a), and 3 more

• Cytokinetics (CYTK)Thesis Intact

  Obstructive hypertrophic cardiomyopathy, Non-obstructive hypertrophic cardiomyopathy, Heart failure with reduced ejection fraction, Heart failure with preserved ejection fraction

• Edgewise Therapeutics (EWTX)Thesis Intact

  Heart failure, Cardiometabolic disease, Hypertrophic cardiomyopathy, Heart failure with preserved ejection fraction

• Editas Medicine (EDIT)Thesis Intact

  Heterozygous familial hypercholesterolemia

• Fractyl Health (GUTS)Thesis Challenged

  Obesity, Type 2 diabetes

• iBio (IBIO)Thesis Intact

  Obesity, PH-HFpEF, Type 2 Diabetes, Cardiometabolic disease, and 1 more

• Immunocore (IMCR)Thesis Intact

  Type 1 diabetes

• Insight Molecular Diagnostics (IMDX)Thesis Challenged

  Heart transplant rejection

• Intellia Therapeutics (NTLA)Thesis Intact

  ATTR amyloidosis with cardiomyopathy

• Ionis Pharmaceuticals (IONS)Thesis Intact

  Severe hypertriglyceridemia, Familial chylomicronemia syndrome, Lp(a)-driven cardiovascular disease, Transthyretin amyloid cardiomyopathy

• Kiniksa Pharmaceuticals International (KNSA)Thesis Intact

  Recurrent pericarditis

• Lexeo Therapeutics (LXEO)Thesis Intact

  FA cardiomyopathy, Hypertrophic cardiomyopathy, Arrhythmogenic cardiomyopathy, PKP2-associated arrhythmogenic cardiomyopathy

• Lineage Cell Therapeutics (LCTX)Thesis Intact

  Type 1 diabetes mellitus

• Lipocine (LPCN)Thesis Broken

  Obesity, Obesity management

• MeiraGTx (MGTX)Thesis Intact

  Obesity

• Mesoblast (MESO)Thesis Intact

  End-stage heart failure with reduced ejection fraction, End-stage ischemic heart failure with reduced ejection fraction

• Metagenomi Therapeutics (MGX)Thesis Intact

  Cardiometabolic diseases

• Microbot Medical (MBOT)Thesis Intact

  Peripheral vascular disease

• Milestone Pharmaceuticals (MIST)Thesis Challenged

  PSVT, Paroxysmal supraventricular tachycardia, Atrial fibrillation with rapid ventricular rate

• Monte Rosa Therapeutics (GLUE)Thesis Intact

  Coronary artery disease, Atherosclerotic cardiovascular disease

• Nektar Therapeutics (NKTR)Thesis Intact

  Type 1 diabetes mellitus

• Neumora Therapeutics (NMRA)Thesis Intact

  Obesity, Cardiometabolic disease

• NewAmsterdam Pharma Company (NAMS)Thesis Intact

  Hypercholesterolemia, High-risk with coronary plaque, Type 2 diabetes or metabolic syndrome, Atherosclerotic cardiovascular disease, and 2 more

• NewcelX (NCEL)Thesis Challenged

  Type 1 Diabetes, Insulin-dependent diabetes

• Palatin Technologies (PTN)Thesis Challenged

  Obesity, Hypothalamic obesity

• Rocket Pharmaceuticals (RCKT)Thesis Intact

  Dilated cardiomyopathy, Arrhythmogenic cardiomyopathy, PKP2-arrhythmogenic cardiomyopathy, BAG3-associated dilated cardiomyopathy

• SAB Biotherapeutics (SABS)Thesis Intact

  Type 1 diabetes, Autoimmune type 1 diabetes

• Sana Biotechnology (SANA)Thesis Challenged

  Type 1 diabetes

• Silence Therapeutics (SLN)Thesis Intact

  Obesity, Dyslipidemia, Hypercholesterolemia, Cardiovascular disease, and 1 more

• Structure Therapeutics (GPCR)Thesis Intact

  Obesity, Obesity or overweight, Type 2 diabetes mellitus, Obesity or overweight with type 2 diabetes

• Tiziana Life Sciences (TLSA)Thesis Challenged

  Type 1 diabetes

• Tonix Pharmaceuticals (TNXP)Thesis Challenged

  Adolescent obesity

• Ultragenyx Pharmaceutical (RARE)Thesis Challenged

  Homozygous familial hypercholesterolemia

• Viking Therapeutics (VKTX)Thesis Intact

  Obesity, Type 2 diabetes

• vTv Therapeutics (VTVT)Thesis Intact

  Diabetes, Type 1 diabetes, Type 2 diabetes, Adjunctive to insulin, and 1 more

• Xeris Biopharma (XERS)Thesis Intact

  Hypoglycemia

• Zura Bio (ZURA)Thesis Intact

  Type 1 diabetes mellitus

Drug pages

AficamtenVK2735

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