Liver and digestive diseases

Companies

• ABIVAX Société Anonyme (ABVX)Thesis Intact

  Crohn's disease, Ulcerative colitis

• Aclaris Therapeutics (ACRS)Thesis Intact

  Eosinophilic esophagitis

• Altimmune (ALT)Thesis Intact

  Alcohol-associated liver disease, Metabolic dysfunction-associated steatohepatitis

• Aquestive Therapeutics (AQST)Thesis Challenged

  Nausea and vomiting

• Arcus Biosciences (RCUS)Thesis Intact

  Inflammatory bowel disease

• Ardelyx (ARDX)Thesis Challenged

  Chronic idiopathic constipation, Irritable bowel syndrome with constipation

• Arrowhead Pharmaceuticals (ARWR)Thesis Intact

  Alcohol-related liver disease, Metabolic-dysfunction associated steatohepatitis

• Assembly Biosciences (ASMB)Thesis Intact

  Primary biliary cholangitis, Primary sclerosing cholangitis

• Chemomab Therapeutics (CMMB)Thesis Challenged

  Nonalcoholic steatohepatitis, Primary sclerosing cholangitis

• Eledon Pharmaceuticals (ELDN)Thesis Challenged

  Liver transplantation

• Equillium (EQ)Thesis Intact

  Celiac disease, Ulcerative colitis

• Eupraxia Pharmaceuticals (EPRX)Thesis Intact

  Eosinophilic esophagitis

• Heron Therapeutics (HRTX)Thesis Challenged

  Postoperative nausea and vomiting, Chemotherapy-induced nausea and vomiting

• Inventiva (IVA)Thesis Challenged

  MASH with moderate and advanced fibrosis (F2/F3), Metabolic dysfunction-associated steatohepatitis

• Ironwood Pharmaceuticals (IRWD)Thesis Intact

  SBS-IF, Short bowel syndrome, Functional constipation, Dependent on parenteral support

• Lipocine (LPCN)Thesis Broken

  Cirrhosis

• Lucid Diagnostics (LUCD)Thesis Challenged

  GERD, Esophageal precancer

• Mesoblast (MESO)Thesis Intact

  Life-threatening gastrointestinal bleeding

• Palatin Technologies (PTN)Thesis Challenged

  Ulcerative colitis

• Palisade Bio (PALI)Thesis Intact

  Crohn's disease, Ulcerative colitis

• ProQR Therapeutics (PRQR)Thesis Intact

  Biliary atresia, Cholestatic disease, Cholestatic liver disease, Metabolic Associated Steatohepatitis, and 1 more

• Protara Therapeutics (TARA)Thesis Intact

  Parenteral support dependence

• Recursion Pharmaceuticals (RXRX)Thesis Intact

  Familial adenomatous polyposis

• Sagimet Biosciences (SGMT)Thesis Intact

  Metabolic dysfunction-associated steatohepatitis, Metabolic dysfunction-associated steatohepatitis cirrhosis

• Shattuck Labs (STTK)Thesis Intact

  Crohn's disease, Inflammatory bowel disease

• Viking Therapeutics (VKTX)Thesis Intact

  MASH

Upcoming catalysts