TNXPTonix Pharmaceuticals Holding Corp.

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ChallengedLast material event Oct 15, 2026 · Updated Oct 25, 2026

Tonmya sales grew again in the third quarter, but cash lasts only into 2027

Tonix Pharmaceuticals sells Tonmya, an approved under-the-tongue tablet for fibromyalgia, and is developing drugs for depression, Lyme disease prevention and other conditions.

Tonix's case rests on Tonmya, a sublingual cyclobenzaprine tablet for fibromyalgia launched in November 2025. Net revenue was about $11.0 million in the second quarter and an estimated $14.0 to $15.0 million in the third. Coverage reaches about 166 million lives, and the sales force grew to about 150. Tonix says cash lasts into early second quarter 2027 and states substantial doubt about continuing. Dr. Reddy's filed a generic challenge to Tonmya's patents in October.

Thesis checklist

1 risk needs attention

Select a row for evidence
Tonmya sales keep growing each quarterSupportedNext: Final third-quarter results and fourth-quarter sales.

Why it is in this state

The evidence, what would weaken it and the source filing

Tonix funds itself until Tonmya pays its wayAt riskNext: The runway statement in the third-quarter 10-Q.

Why it is in this state

The evidence, what would weaken it and the source filing

Tonmya's patents hold off a genericAwaiting evidenceNext: Whether Tonix sues by mid-November 2026.

Why it is in this state

The evidence, what would weaken it and the source filing

HORIZON tests the drug in depressionAwaiting evidenceNext: Enrollment progress and a topline date.

Why it is in this state

The evidence, what would weaken it and the source filing

Next decision point

Fourth-quarter 2026 Tonmya sales

Tests: Tonmya sales keep growing each quarter

Fourth-quarter 2026 report

Does Tonmya revenue keep rising beyond the third quarter's estimated $14 to $15 million as new coverage starts?

Strong, inconclusive and weak outcomes

What to look for in the result and how each would move the checklist

Questions to investigate

History

Price and material events

Select an event marker to read the update below. Marker colors show Thesis status.

ChallengedCurrentFinancial
-5.9%Oct 15, 2026

Tonmya sales grew again in the third quarter, but cash lasts only into 2027

About this history: every entry shows when the Thesis moved and what it said. The reasoning behind each move (the evidence, the analysis and the source filing) and the earnings write-ups are part of a subscription.

Pipeline

Cocaine intoxication
TNX-1300 · 1 upcoming
FDA Meeting
2026
Kidney transplant rejection prophylaxis
TNX-1500 · 1 upcoming
Phase 2 Study InitiationIIT
2H 2026
Lyme disease prevention
TNX-4800 · 3 upcoming · 1 completed
Phase 2 Study Initiation
Q1 2027
Phase 2 Data
TBD
Phase 2 Study Initiation
2028
Acute stress disorder· acute stress reaction
TNX-102 SL · 1 upcoming
Phase 2 Data: ToplineOASISIIT
Mid 2027
Smallpox and mpox prevention
TNX-801 · 1 upcoming
Phase 1 Study Initiation
Mid 2027
Prader-Willi syndrome· pediatric and adolescent
TNX-2900 · 1 upcoming
Phase 2 Study Initiation
2H 20272H 2027
Chronic neuropathic pain
TNX-4900 · 1 upcoming
IND-enabling studies for chronic neuropathic pain
TBD
Migraine
TNX-1900 · 1 upcoming
Phase 1 DataIIT
TBD
Gastric and colorectal cancer· in combination with PD-1 blockade
TNX-1700 · 1 upcoming
IND Submission
TBD
Immuno-oncology (multiple cancers)
TNX-4700 · 1 upcoming
(anti-BTLA mAb) IND-enabling development in immuno-oncology
TBD
Major depressive disorder
TNX-102 SL · 1 upcoming · 2 completed
Phase 2 DataHORIZON
TBD
Fibromyalgia
TNX-102 SL · 1 completed
Commercial Launch
Nov 17, 2025

Dates, trials and completed outcomes are open to everyone. What each upcoming milestone hinges on is part of a subscription.

Quick answers

Is the Tonix Pharmaceuticals (TNXP) investment thesis intact?
It is under pressure. Readouts currently rates the Tonix Pharmaceuticals Thesis Challenged. Tonmya sales grew again in the third quarter, but cash lasts only into 2027.
What is the next catalyst for Tonix Pharmaceuticals (TNXP)?
The next dated event is Phase 2 start for TNX-1500, expected 2H 2026, as stated by the company. Also ahead: Phase 2 start for TNX-4800, expected Q1 2027.

Competitive landscape

1 peers tracked

For informational purposes only—not investment advice. Always conduct your own research before making investment decisions.

Financial snapshot

Dates and calculation details

Cash: Market-data provider estimate; measurement period unavailable.

Debt: Market-data provider estimate; a complete comparable filing balance is unavailable.

Quarterly burn: Estimated from trailing free cash flow; measurement period unavailable.

Net cash and estimated runway require verified matching measurement periods. Missing debt components are not assumed to be zero.

Runway: No underlying guidance available.