PSNLPersonalis, Inc.

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IntactLast material event Aug 4, 2026 · Updated Oct 25, 2026

Tempus's $16.25-a-share acquisition of Personalis cleared U.S. antitrust review in October; the shareholder vote is the main step left

Personalis sells NeXT Personal, a blood test that tracks cancer's return, and genomic services to drug companies; it has agreed to be acquired by Tempus AI.

Personalis has agreed to be acquired by Tempus AI for $16.25 a share in Tempus stock. At or below a Tempus price of $48.42 the exchange ratio is fixed, so the value falls if Tempus trades lower. The antitrust waiting period expired on October 2, 2026, leaving the Personalis shareholder vote, whose date has not been set, as the main step. Merck, with about 13% of the vote, has agreed to vote in favor, and the outside date is April 20, 2027.

Thesis checklist

0 risks need attention

Select a row for evidence
Shareholders approve the mergerAwaiting evidenceNext: Meeting date and vote result.

Why it is in this state

The evidence, what would weaken it and the source filing

U.S. antitrust clearanceSupportedNext: Closing.

Why it is in this state

The evidence, what would weaken it and the source filing

Tempus shares hold above the $48.42 floorAwaiting evidenceNext: Tempus's share price before closing.

Why it is in this state

The evidence, what would weaken it and the source filing

NeXT Personal keeps growingSupportedNext: Q3 volumes.

Why it is in this state

The evidence, what would weaken it and the source filing

Next decision point

Shareholder vote

Tests: Shareholders approve the merger

Date not yet announced

Do Personalis shareholders approve the Tempus merger?

Strong, inconclusive and weak outcomes

What to look for in the result and how each would move the checklist

Questions to investigate

History

Price and material events

Select an event marker to read the update below. Marker colors show Thesis status.

IntactCurrentCommercial
+2.4%Aug 4, 2026

Tempus's $16.25-a-share acquisition of Personalis cleared U.S. antitrust review in October; the shareholder vote is the main step left

IntactCorporate
-13.3%Jul 20, 2026

Personalis's $1.5B all-stock Tempus acquisition: MRD platform finds a buyer, but deal closing conditions determine whether holders get paid

ChallengedCommercial
+12.9%May 20, 2026

Medicare coverage cascade unlocks MRD commercial ramp, but $233M burns fast against $10M clinical revenue

About this history: every entry shows when the Thesis moved and what it said. The reasoning behind each move (the evidence, the analysis and the source filing) and the earnings write-ups are part of a subscription.

Pipeline

Merger with Tempus AI
Tempus merger · 3 upcoming · 1 completed
Form S-4 registration statement effectiveness
TBD
Nasdaq listing approval for Parent stock
TBD
Personalis stockholder approval vote on
TBD
Cancer recurrence surveillance· breast and lung cancer
NeXT Personal · 1 completed
Clinical revenue growth target of 5x in 2026
Reported May 7, 2026
Additional indications (beyond breast cancer)
NeXT Personal · 1 completed
Medicare coverage decision for additional indication(s)
Reported Feb 26, 2026
Early-stage breast cancer
NeXT Personal · 1 completed
Medicare coverage decision
Reported Jan 8, 2026

Dates, trials and completed outcomes are open to everyone. What each upcoming milestone hinges on is part of a subscription.

Quick answers

Is the Personalis (PSNL) investment thesis intact?
Yes. Readouts currently rates the Personalis Thesis Intact. Tempus's $16.25-a-share acquisition of Personalis cleared U.S. antitrust review in October; the shareholder vote is the main step left.
How long will Personalis' cash last?
Personalis has said its cash will fund operations for at least the next 12 months (guidance as of November 4, 2026).

Other companies we cover in these diseases

Early-stage breast cancer
Context Therapeutics (CNTX)

Disease areas: Lung cancer, Breast and gynecologic cancers
Catalyst calendar · Upcoming FDA decisions · Thesis changes

For informational purposes only—not investment advice. Always conduct your own research before making investment decisions.

Financial snapshot

Dates and calculation details

Cash: Market-data provider estimate; measurement period unavailable.

Debt: Market-data provider estimate; a complete comparable filing balance is unavailable.

Quarterly burn: Estimated from trailing free cash flow; measurement period unavailable.

Net cash and estimated runway require verified matching measurement periods. Missing debt components are not assumed to be zero.

Runway: No underlying guidance available.