JSPRJasper Therapeutics, Inc.

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Market reactionShares rose 20% on Nov 6.

ChallengedLast material event Oct 15, 2026 · Updated Oct 25, 2026

Jasper needs stockholders to approve its $132 million preferred conversion; IgAN data due

Jasper Therapeutics is a clinical-stage company developing immune-disease drugs, led by the complement inhibitor vensobafusp alfa (KP104) and the anti-KIT antibody briquilimab; none of its products is approved.

After acquiring Kira Pharmaceuticals in July, Jasper's lead program is vensobafusp alfa (KP104), a biologic that blocks two complement pathways. Its Phase 2 renal basket study in China has enrolled 18 IgA nephropathy patients, with initial data due by year-end. Jasper also plans an FDA end-of-Phase 2 meeting in PNH. Briquilimab is moving toward a pre-BLA meeting in SCID, with next steps due in early 2027. A $132 million private placement of preferred stock funds plans through 2H 2028, if stockholders approve its conversion.

Thesis checklist

1 risk needs attention

Select a row for evidence
Stockholders approve converting the preferred stockAt riskNext: Special stockholder meeting on the conversion.

Why it is in this state

The evidence, what would weaken it and the source filing

Vensobafusp alfa shows early activity in IgA nephropathyAwaiting evidenceNext: Initial IgAN interim data (by year-end 2026).

Why it is in this state

The evidence, what would weaken it and the source filing

FDA agrees a late-stage path in PNHAwaiting evidenceNext: End-of-Phase 2 meeting outcome (first half of 2027).

Why it is in this state

The evidence, what would weaken it and the source filing

Briquilimab's SCID data support a BLAAwaiting evidenceNext: Next steps after the FDA meeting (first quarter of 2027).

Why it is in this state

The evidence, what would weaken it and the source filing

Next decision point

Initial IgAN data from the renal basket study

Tests: Vensobafusp alfa shows early activity in IgA nephropathy

By year-end 2026

Does vensobafusp alfa show early efficacy and acceptable safety in IgAN at a practical subcutaneous schedule?

Strong, inconclusive and weak outcomes

What to look for in the result and how each would move the checklist

Questions to investigate

History

Price and material events

Select an event marker to read the update below. Marker colors show Thesis status.

ChallengedCurrentClinical
-9.8%Oct 15, 2026

Jasper needs stockholders to approve its $132 million preferred conversion; IgAN data due

ChallengedFinancial
-5.5%Oct 1, 2026

Merged Jasper/Kira bets a $132M raise on briquilimab's pre-BLA path in SCID, conditional on FDA accepting existing single-arm data as registrational

IntactCorporate
-2.6%Aug 26, 2026

Post-merger anti-KIT antibody eyes pre-BLA filing in SCID, but Nasdaq delisting notice and going-concern doubt test whether $132M PIPE actually reaches it

ChallengedCorporate
+14.3%Jul 16, 2026

Jasper-Kira merger resets the clock with $132M and a three-program pipeline, but briquilimab's pre-BLA path in SCID must validate before KP-104's Phase 3 case is built

About this history: every entry shows when the Thesis moved and what it said. The reasoning behind each move (the evidence, the analysis and the source filing) and the earnings write-ups are part of a subscription.

Pipeline

IgA nephropathy
vensobafusp alfa · 1 upcoming
Phase 2 Data: Interim
By year-end 2026
Severe Combined Immunodeficiency (SCID)
briquilimab · 1 upcoming
Pre-BLA Meeting
Q1 2027
Autoantibody-mediated disorders
KP-701 · 2 upcoming
IND Submission
Q1 2027
Phase 1 Data
Q3 2027
Focal segmental glomerulosclerosis
vensobafusp alfa · 1 upcoming
Phase 2 Study Initiation
Q1 2027
Paroxysmal nocturnal hemoglobinuria (PNH)
vensobafusp alfa · 1 upcoming
End-of-Phase Meeting
H1 2027
Rare renal disorders· IgAN, C3G, FSGS
vensobafusp alfa · 1 upcoming
Phase 2 Data: Interim
Q2 2027
CSU· CIndU
briquilimab · 1 completed
DataBEACON
Reported Jan 8, 2026
Allergic asthma
briquilimab · 1 completed
Data: InterimETESIAN
Reported Dec 2, 2025
Cold urticaria
briquilimab · 1 completed
Phase 1b/2a DataSPOTLIGHT
Reported Jun 16, 2025

Dates, trials and completed outcomes are open to everyone. What each upcoming milestone hinges on is part of a subscription.

Quick answers

Is the Jasper Therapeutics (JSPR) investment thesis intact?
It is under pressure. Readouts currently rates the Jasper Therapeutics Thesis Challenged. Jasper needs stockholders to approve its $132 million preferred conversion; IgAN data due.
What is the next catalyst for Jasper Therapeutics (JSPR)?
The next dated event is Phase 2 interim results for Vensobafusp alfa, expected By year-end 2026, as stated by the company. Also ahead: IND submission for KP-701, expected Q1 2027.
How long will Jasper Therapeutics' cash last?
Jasper Therapeutics has said its cash will fund operations into H2 2028 (guidance as of August 14, 2026). It reported $143 million in cash as of June 30, 2026.

Competitive landscape

9 peers tracked

For informational purposes only—not investment advice. Always conduct your own research before making investment decisions.

Financial snapshot

Dates and calculation details

Cash: Market-data provider estimate; measurement period unavailable.

Debt: Market-data provider estimate; a complete comparable filing balance is unavailable.

Quarterly burn: Estimated from trailing free cash flow; measurement period unavailable.

Net cash and estimated runway require verified matching measurement periods. Missing debt components are not assumed to be zero.

Runway: No underlying guidance available.